The 21st century’s central economic nexus will be centred on the Indo-Pacific region. Simultaneously, the intensifying US-China competition in the Indo-Pacific is deepening. Regional middle powers must negotiate this competition to ensure their interests remain intact. This article applies a realist framework to analyse the strategic alignment of Australia, Japan, and India in response to the great power competition. It examines the strategy each middle power is pursuing to protect their interests and the motivations behind their approaches. It finds a convergence in middle power interests centred on maritime behaviour, adherence to international law, and investment in regional institutions.